ホウチン テルヒサ
Teruhisa Hochin
寶珍 輝尚 所属 追手門学院大学 理工学部 情報工学科 職種 教授 |
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発行・発表の年月 | 2021/06/20 |
形態種別 | 論文 |
査読 | 査読あり |
標題 | Extraction of ncRNAs Associated with Liver Cancer Using Machine Learning. |
執筆形態 | 共著・編著(代表編著を除く) |
掲載誌名 | ACIT 2021: The 8th International Virtual Conference on Applied Computing & Information Technology(ACIT) |
掲載区分 | 国外 |
出版社・発行元 | ACM |
巻・号・頁 | 81-86頁 |
著者・共著者 | Koshiro Sekine,Teruhisa Hochin,Hiroki Nomiya |
概要 | In this paper, we used a random forest for the NBDC liver cancer dataset to extract non-coding RNAs (ncRNAs) which are considered to be associated with liver cancer from a huge amount of ncRNAs. The explanatory variables for the random forest were the expression levels of ncRNAs, and the objective variable was non-tumor tissue or tumor tissue. The expression level calculation tool, kallisto, was used to extract the expression levels of ncRNAs. Since there are a huge number of ncRNAs, we used a statistical hypothesis test for their expression levels and used only ncRNAs that were significantly different between non-tumor tissues and tumor tissues as explanatory variables. As a result, we succeeded in extracting ten ncRNAs that are considered to be associated with liver cancer. |
DOI | 10.1145/3468081.3471127 |
DBLP ID | conf/acit2/SekineHN21 |
PermalinkURL | https://dblp.uni-trier.de/rec/conf/acit2/2021 |
researchmap用URL | https://dblp.uni-trier.de/db/conf/acit2/acit2021.html#SekineHN21 |