タカハシ　ヒデユキ   Hideyuki Takahashi   高橋　英之    所属   追手門学院大学  理工学部 情報工学科    職種   准教授
言語種別	英語
発行・発表の年月	2018/10
形態種別	論文
査読	査読あり
標題	Neural basis of altered earlier attention and higher order biological motion processing in schizophrenia.
執筆形態	共著・編著（代表編著を除く）
掲載誌名	Social neuroscience
掲載区分	国外
巻・号・頁	13(5),pp.594-601
著者・共著者	Yukiko Matsumoto,Hideyuki Takahashi,Jun Miyata,Genichi Sugihara,Toshiya Murai,Hidehiko Takahashi
概要	Schizophrenia patients have impairments of biological motion (BM) perception, which provides critical information about social cognition. Because social cognition is underpinned by attention, the impairments of BM perception in schizophrenia could be partially attributable to altered attention. To elucidate the impairments in attention and social perception in schizophrenia, we investigated the neural basis of impaired BM processing using MRI in respect to attention deficits by eye tracker. Voxel-based morphometry was performed to evaluate the relationship between BM perception and gray matter (GM) volume. The temporo-parietal junction (TPJ) and anterior superior temporal sulcus (aSTS) were related to task accuracy. However, when the effect of attention (i.e., eye movement) was controlled, the relationship in TPJ became non-significant, while aSTS showed a significant relationship with BM perception. Alteration in TPJ might be associated with inefficient attentional strategy, whereas dysfunctional aSTS might be correlated with deficit in higher order BM processing per se. Several cognitive levels as well as corresponding brain areas are possibly involved in the manifestation of social cognitive deficits in schizophrenia.
DOI	10.1080/17470919.2017.1366363
ISSN	1747-0919
PMID	28805504